NAFLD Fibrosis Score Calculator

Estimate NAFLD fibrosis risk using age, BMI, diabetes status, AST/ALT ratio, platelets, and albumin.

878.3K uses Updated · 2026-05-25 Runs locally · zero upload
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How to Use the NAFLD Fibrosis Score Calculator

Enter age, BMI, diabetes or impaired fasting glucose status, AST, ALT, platelet count, and albumin. Use labs from the same clinical window whenever possible.

The calculator returns the NAFLD Fibrosis Score and classifies it using common cutoffs: below -1.455 suggests low risk, above 0.676 suggests high risk, and the middle range is indeterminate.

Formula and Method - NAFLD Fibrosis Score Calculator

NFS = -1.675 + 0.037×age + 0.094×BMI + 1.13×diabetes/IFG + 0.99×(AST/ALT) - 0.013×platelets - 0.66×albumin

The score combines demographic, metabolic, liver enzyme, platelet, and albumin signals. Higher AST/ALT ratio, lower platelets, and lower albumin generally push the score upward.

Use Cases for the NAFLD Fibrosis Score Calculator

  • Initial noninvasive fibrosis risk screening in people with suspected NAFLD.
  • Following how changes in weight or labs alter risk classification over time.
  • Explaining why aminotransferases alone do not fully describe fibrosis risk.

Frequently asked questions about NAFLD Fibrosis Score Calculator

What platelet unit is expected?

Use platelet count in 10^9/L, such as 220 for 220×10^9/L.

What does indeterminate mean?

The score does not clearly rule out or rule in advanced fibrosis, so additional assessment is usually needed.

Does the diabetes field include IFG?

Yes. The original variable covers diabetes or impaired fasting glucose.